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Prevent IAP For Improved IAQ
Significant Health Effects of Indoor Pollutants

Indoor air pollution can impact human health in a variety of ways, from irritant effects to respiratory disease, cancer and premature death. Indoor air pollutants can be elevated to levels that may result in adverse health effects.

The health impacts of greatest significance include asthma, cancer, premature death, respiratory disease and symptoms, and irritant effects, according to the California Air Resources Board (CARB).

Modern society includes many tradeoffs, often characterized through risk/benefit analyses.
Many indoor pollutants cause eye, nose, throat and respiratory tract irritation. Aldehydes, as well as some other VOCs and oxidants, are known mucous membrane irritants. Formaldehyde is the most commonly identified irritant.

Acute effects of irritant chemicals can include respiratory and eye irritation, headache, difficulty breathing, and nausea. Some of these effects, particularly respiratory symptoms and eye, nose and throat irritation can also be experienced with chronic exposure.

Terpenes, such as pinene and limonene, frequently used in cleaning products for their favorable odor characteristics and solvent properties, react with indoor oxidants to produce formaldehyde and ultra fine particulate matter.

The impact on health depends on the toxicological properties of the chemical and the exposure and absorbed dose an individual may receive.

Particulate matter
Particulate matter (PM) is a complex mixture of very small particles and other non-gaseous materials suspended in the air. Indoor particle sources include combustion devices such as woodstoves and fireplaces, and activities such as smoking, cooking, candle burning, and vacuuming, all of which can produce PM with harmful components similar to those found in outdoor air. Indoor particles also include fibrous materials, pollen, mold spores and fragments, and tracked-in soil particles. Pollens and mold can trigger allergies and asthma.

Tracked-in particles and some particles from combustion sources become trapped in carpets and have been shown to include a mix of toxic components such as polycyclic aromatic hydrocarbons (PAHs) and lead.

Carbon monoxide
Carbon monoxide (CO) is a colorless, odorless gas that causes flu-like symptoms (headache, nausea, lethargy) and inability to concentrate, at lower exposure levels over periods of time. At very high levels, CO can cause unconsciousness and even death. CO is a product of incomplete combustion, emitted from sources such as vehicle exhaust, gas and propane stoves and
furnaces, woodstoves, kerosene heaters and cigarettes.

Very high levels of CO occur relatively infrequently indoors. However, a California study of death certificates showed that about 30 to 40 deaths occurred in California each year, on average, due to unintentional CO poisoning. About two thirds of those deaths were attributable to indoor sources.

The indoor sources most implicated in past CO poisonings were combustion appliances,
such as malfunctioning or poorly tuned gas or propane furnaces and stoves, and the improper use of charcoal grills and hibachis indoors (contrary to warnings). Motor vehicles, such as those
unwisely left running in a garage, also have taken a substantial toll. The relevant literature also indicates that other CO health effects occur: hundreds of emergency room visits and thousands of misdiagnosed flu-like illnesses due to non-fatal CO poisoning are estimated to occur each year.

Toxic Air Contaminants and
Other Indoor Air Pollutants

Pollutants that may contribute to an increase in death or serious illness can occur at elevated levels indoors due to emissions from indoor sources. Some have been identified by CARB as toxic air contaminants (TACs), air pollutants that don’t meet traditional criteria for pollutants.
• Volatile organic compounds (VOCs), such as formaldehyde and chlorinated solvents
are common in indoor air, and can exacerbate asthma and cause cancer and irritant effects.

Some of these chemicals also have reproductive, developmental and neurological effects at very high levels encountered infrequently in non-industrial workplaces.

Indoor levels of formaldehyde, a pungent smelling gas, nearly always exceed health based
guideline levels and acceptable cancer risk levels.

Formaldehyde is emitted from numerous indoor sources including building materials (especially pressed wood products), composite wood furnishings, personal care products, cosmetics, permanent pressed clothing, combustion sources, and some new carpet pads and adhesives.
• Environmental tobacco smoke (ETS) causes cancer, heart disease, asthma episodes, middle ear infections in children, sudden infant death syndrome and other adverse effects. Despite decreases in the percent of smokers in the population and the statewide prohibition of
smoking in workplaces, some individuals, especially children, are still exposed to elevated levels of ETS in the homes and vehicles of smokers.
• Polycyclic aromatic hydrocarbons (PAHs) – PAHs, emitted from combustion sources such as cigarettes, woodstoves and fireplaces, include a number of known or suspected carcinogens. They have been found to adsorb onto particles in the air and deposit onto carpets, from which they can be resuspended during vacuuming or other activity.
• Radon daughters and asbestos are other known lung carcinogens found indoors in some environments. Both radon and asbestos are naturally-occurring, each emanating from specific types of soils.
Radon levels in are typically lower than mitigation guideline levels, according to CARB. However the risk from radon cannot be fully separated from that of tobacco smoke, and reduction of exposure to tobacco smoke remains the primary mitigation approach. Indoor asbestos is elevated only infrequently, typically during remodeling of older buildings.
• Pesticides and metals – Dust from surfaces and carpets in homes and schools have been shown to contain numerous residues of pesticides, lead, mercury and other long-lasting contaminants that have originated from outdoor activities, cigarettes, fireplaces and other
sources. This is of special concern for very young children, who spend time on the floor, and put their hands in their mouths, because ingestion is often the primary route of exposure.

Pesticides are widely used, and some can cause adverse developmental and neurological
effects at elevated exposure levels. Many pesticides registered for use today are short lived, yet some are persistent in the environment, lasting 20 to 30 years or more.
Recent studies indicate that some pesticides may be more persistent in indoor environments,
because they do not experience the effects of weather and sunlight.

Biological Contaminants
Biological contaminants include substances of plant, animal, or microbial origin, such as bacteria, viruses, mold, pollen, house dust mites, animal dander; biological toxins such as endotoxins and mycotoxins, and microbial volatile organic chemicals. These biological
agents are abundant in both indoor and outdoor environments, but are considered contaminants when found in undesired locations or at elevated concentrations. Excessive exposure to these contaminants can be associated with mucous membrane irritation (which may cause symptoms such as itchy eyes, runny nose or sore throat) or hypersensitivity reactions such as asthma attacks or allergy symptoms in sensitive individuals.

Some individuals in persistently damp buildings report a variety of symptoms such as headache, memory difficulties, vomiting, and diarrhea; some researchers postulate that exposure to biological toxins may induce such symptoms. In a 2004 Institute of Medicine report scientists
found a number of symptoms and illnesses associated with dampness in buildings and with indoor mold, although the scientific evidence was not yet considered sufficient to confirm a causal relationship.

Many communicable diseases are primarily transmitted from person to person in indoor air.
Common viral infections such as influenza, measles and chicken pox, as well as emerging diseases such as Severe Acute Respiratory Syndrome (SARS), are spread through inhalation of virus-contaminated droplets produced when an infected person coughs or sneezes, or from
touching a surface or object contaminated with infectious droplets and then touching one’s mouth, nose, or eyes (CDC, 2004). Tuberculosis is a notorious infectious disease that is transmitted in closely occupied spaces.

Building-related illness (BRI) refers to an illness for which the specific cause can be identified within the building, such as bacteria in ventilation systems causing Legionnaires’ disease, or humidifier fever.

The usual causes of BRI include viruses, bacteria, and fungi. BRI impacts can be substantial, and are of increasing interest as the role of buildings in promoting diseases of biological contaminants becomes better understood.

Indoor pollution causes substantial, avoidable illness and health impacts – ranging from irritant effects to asthma, cancer, and premature death – and costs billions of dollars each year. Because there are numerous sources of pollutants in indoor environments, and because people
spend most of their time indoors, exposure and the associated risk are substantial.

Many agencies, professional groups, and organizations have taken actions to reduce indoor pollution, but these have been piecemeal and are not sufficiently effective in addressing the problem, says CARB.

There are many actions that could be taken to significantly reduce indoor emissions and exposure. If experience in controlling sources of outdoor pollution is repeated relative to indoor  sources, many of these measures will be low cost and will provide substantial health benefits. FSM For CARB’s full report on Indoor Air Pollution, go to www.arb.ca.gov/research/indoor/pcs/pcs.htm.  

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